CANCER IMMUNOLOGY. A TRANSLATIONAL MEDICINE CONTEXT. 2ND EDITION

• Introduction on Cancer Immunology and Immunotherapy
• Role of Innate Immunity in Cancers and Antitumor Response
• Tumor-Associated Myeloid Cells in Cancer Progression
• B-Cells in Cancer Immunology: For or Against Cancer Growth?
• The Roles of CD4+ T-Cells in Tumor Immunity
• Regulatory T-Cells and Th17 Cells in Tumor Microenvironment
• T-Cell Metabolism and Its Dysfunction Induced by Cancer
• The Role of Exhaustion in Tumor-Induced T-Cell Dysfunction in Cancer
• The Role of NK Cells in Cancer
• Role of Plasmacytoid Dendritic Cells in Cancer
• The CD95/CD95L Signaling Pathway: A Role in Carcinogenesis
• MHC Class I Molecules and Cancer Progression: Lessons Learned from Preclinical Mouse Models
• Role of Cytokines in Tumor Immunity and Immune Tolerance to Cancer
• Role of Chemokines and Chemokine Receptors in Cancer
• Role of the Inflammasome in Cancer
• Cancer Immunoediting: Immunosurveillance, Immune Equilibrium, and Immune Escape
• Apoptosis and Cancer
• Endoplasmic Reticulum Stress and Autophagy in Cancer
• Prognostic Value of Innate and Adaptive Immunity in Cancers
• Immunogenetics of Cancer
• Epigenetics and MicroRNAs in Cancer
• The Role of DNA Methylation in Cancer
• Immunosenescence, Oxidative Stress, and Cancers
• Nutrition, Immunity, and Cancers
• Inborn Errors of Immunity and Cancers
• Allergies and Cancers
• Envisioning the Application of Systems Biology in Cancer Immunology
• Principles of Immunological Diagnostic Tests for Cancers
• Immunohistochemistry of Cancers
• Fluorescent In Situ Hybridization: Methods and Application in Cancer Diagnosis
• Cancer Molecular and Functional Imaging
• Cancer Imaging with Radiolabeled Monoclonal Antibodies
• Flow Cytometry in Cancer Immunotherapy: Applications, Quality Assurance, and Future

This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel developments in the field.
In the new edition of this very well received book, first published in 2015, the original chapters have been significantly updated and additional chapters included on, for example, current knowledge on the roles of T-helper cells and NK cells in tumor immunity, the part played by oncoviruses in the development of various cancers, and the applications of fluorescent in situ hybridization, bioluminescence, and cancer molecular and functional imaging. Cancer Immunology: A Translational Medicine Context will be of special value to clinical immunologists, hematologists, and oncologists.

Features
• Describes in detail interactions between cancerous cells and various components of the innate and adaptive immune system
• Focuses on clinical aspects in order to educate clinicians in the clinical implications of recent research and new developments
• Updated and revised edition reflecting the latest advances in the field

Author
Nima Rezaei gained his medical degree from Tehran University of Medical Sciences in 2002 and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also undertook a short-term fellowship of Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Since 2010, Dr. Rezaei has worked at the Department of Immunology, School of Medicine, Tehran University of Medical Sciences. He is now the Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences; and co-founder and Deputy President of the Research Center for Immunodeficiencies. He is also the Founding President of Universal Scientific Education and Research Network (USERN). Dr. Rezaei has already been the director of more than 100 research projects and has designed and participated in several international collaborative projects. He is an editorial assistant or board member for more than 40 international journals. He has edited more than 10 books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 700 articles in international scientific journals.