THE EVOLUTION OF IMMUNOTHERAPY AGAINST TUMORS. AN HISTORICAL APPROACH

THE EVOLUTION OF IMMUNOTHERAPY AGAINST TUMORS. AN HISTORICAL APPROACH

Editorial:
ACADEMIC PRESS
Año de edición:
Materia
Oncología
ISBN:
978-0-443-21798-2
Páginas:
194
N. de edición:
1
Idioma:
Inglés
Disponibilidad:
Disponible en 10 días

Descuento:

-5%

Antes:

170,00 €

Despues:

161,50 €

The Evolution of Immunotherapy Against Tumors: An Historical Approach summarizes the literature concerning the development of the theory of immune surveillance against tumors. It discusses the evidence for and against this theory, along with the concept of immunoediting. Finally, current approaches in anti-tumor immunotherapy will be analyzed.

The immune system plays a major role in the surveillance against tumors. To avoid attack from the immune system, tumor cells develop different strategies to escape immune surveillance. Evidence of immune surveillance comes from both animal models and clinical observations. Mice with a wide variety of immunodeficiencies have a high rate of tumor incidence and are more susceptible to transplanted or chemical carcinogen-induced tumors. Immunosuppressed patients have a high incidence of tumors. However, many patients develop cancer even in the presence of an apparently normal immune system. This indicates that tumor cells can escape immune surveillance.

Features:
• Covers the experimental approaches to investigate immunotherapy against tumors
• Provides a comprehensive overview of the pharmacological tools in this field
• Serves as a reference book to researchers in the respective fields and related disciplines

Author
Domenico Ribatti, Full Professor of Human Anatomy, University of Bari Medical School, Bari, Italy