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124,49 €This volume provides a comprehensive and multi-disciplinary overview of the aging lung, written by the main researchers in the field. Current physiological, cellular and molecular understanding of how the lungs age and the relationship to age-associated lung diseases will be presented. The contents are aimed at a broad audience of scientists and clinicians with an interest in the respiratory system, pathogenesis of age-associated lung diseases and clinical implications.
Contents:
•Normal Development, Anatomy, Histology and Aging of the Lung (Xuchen Zhang and Robert J Homer)
•Physiology of the Aging Lung (Brienne Miner, Thomas M Gill, and Carlos A Vaz Fragoso)
•Aging Lung, Environmental and Genetic Factors — Race, Ethnicity and Gender (Holly Keyt, Stephanie Levine, and Claude Jourdan Le Saux)
•Frailty in Pulmonary and Critical Care Medicine (Cristine E Berry and Enid R Neptune)
•Intensive Care Unit Outcomes in Older Adults (Margaret A Pisani and Lauren Ferrante)
•Severe Sepsis, Pneumonia and Aging (Olufunmilayo Falade and Sachin Yende)
•Sepsis and Acute Lung Injury in Aging (Anup Srivastava, Yao Wong, Shruti Erramilli, and Praveen Mannam)
•Acute Respiratory Distress Syndrome: The Role of Mesenchymal Stem Cells and Arising Complications Due to an Aging Lung (John Sembrat, Maria G Kapetanaki, and Mauricio Rojas)
•The Aging Immune System, Vaccine Efficacy, and the Lung (Jenna M Bartley and Laura Haynes)
•Respiratory Infection, Airway Colonization and Chronic Inflammation in Aging (Chad Marion and Charles S Dela Cruz)
•HIV, the Lung and Aging (Lynn M Schnapp and Kristina Crothers)
•Geriatric Pulmonary Hypertension: Recent Epidemiologic Trends and Treatment Update (Vanessa Yap, George A Kuchel, and Raymond J Foley)
•Growth Factors and Aging in Pulmonary Arterial Hypertension (Claudio Bravo, Won-Kyung Cho, and Hyung J Chun)
•Chronic Obstructive Lung Disease in the Elderly (Jessica F Most and Carolyn L Rochester)
•Genomics of Lung Aging and Idiopathic Pulmonary Fibrosis (Brenda Juan-Guardela and Naftali Kaminski)
•Potential Mechanistic Links Between Aging and IPF (Hongyi Pan, Mridu Gulati, and Erica L Herzog)
•Telomeres and Telomerase (Mary Armanios)
•Endoplasmic Reticulum Stress (Marta Bueno and Ana L Mora)
•Autophagy and Metabolism (Jaime L Schneider and Cecilia G Sanchez)