STEM CELLS HANDBOOK. 2ND EDITION

1. Introduction to Stem Cells
2. Contemporary Ethical Issues in Stem Cell Research
3. Stem Cells from Early Mammalian Embryos
4. Quantitative Approaches to Model Pluripotency and Differentiation in Stem Cells
5. Growth Dynamics of Fetal Human Neural Stem Cells
6. Immunobiology of Embryonic and Induced Pluripotent Stem Cell Transplantation
7. Urodele Limb Regeneration: Mechanisms of Blastema Formation and Growth
8. Mechanism of miR-302-Mediated iPS Cell Generation
9. Bioreactor Expansion of Pluripotent Stem Cells
10. Generation of Hepatocyte-Like Cells from Human Pluripotent Stem Cells
11. Neural Differentiation from Pluripotent Stem Cells
12. Generation of Anterior Foregut Derivatives from Pluripotent Stem Cells
13. Commercial Opportunities for Induced Pluripotent Stem Cells
14. Spermatogonial Stem Cells in Adult Mice and Men
15. Characterization of the Hematopoietic Stem Cell Niche: Cellular and Molecular Analysis
16. Glandular Stem Cells (GSCs): Stem Cells in Glandular Organs
17. Human Mammary Epithelial Stem/Progenitor Cells
18. Mammary Epithelial Stem Cells
19. Gastric Stem Cell Biology: Proliferation Kinetics, Differentiation Hierarchies, and Role in Carcinogenesis
20. Progenitors of Islet Cells
21. Stem Cell Populations Giving Rise to Liver, Biliary Tree, and Pancreas
22. Liver Regeneration in Health and Disease
23. Human-Induced Pluripotent Stem Cells, Embryonic Stem Cells, and Their Cardiomyocyte Derivatives: An Overview
24. Potential of Glial Cells
25. Stem Cells and Aging
26. Translating Stem Cell Discoveries
27. Mesenchymal Stromal/Stem Cell Transplantation: From Tissue Regeneration to Immune Modulation
28. Stem Cells and Tissue Engineering in Burns and Wounds
29. Derivation of Retinal Pigmented Epithelial Cells for the Treatment of Ocular Disease
30. Stem Cells and Diabetes
31. Cancer Is a Problem of Developmental Biology: Maturation Arrest and the Hierarchical Model of the Origin of Cancer from Stem Cells
32. Targeting the Stem Cell Plasticity of Tumor Cells
33. Molecular Evolution of Leukemia Stem Cells
34. Rodent Models for Assessing the Role of Stem Cells in Liver Development, Regeneration, and Carcinogenesis
35. Breast Cancer Stem Cells: From Theory to Therapy
36. Nephroblastoma/Wilms Tumor: A Corrupted Cap Stem Cell Caricature

This book discusses critical areas of progress in stem cell research, including the most recent research and applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells. The text covers basic knowledge of stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, the technology of obtaining appropriate cells for transplantation as well as the role of stem cells in cancer and how therapy may be directed to cancer stem cells. This new volume is essential reading for all scientists currently in the field or allied research areas, and those for those graduate students who envision a career in stem cells.

Features
• Discusses progress in stem cell research, including applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells
• Covers topics such as stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, and the technology of obtaining appropriate cells for transplantation
• Explores the role of stem cells in cancer and how therapy may be directed to cancer stem cells

Author
Dr. Sell is a board certified pathologist and immunologist. He began research in 1957 while a medical student at the University of Pittsburgh, in the Department of Pathology, under Frank J. Dixon. After a pathology residency at Massachusetts Hospital, and post doctoral fellowships at NIH and Birmingham England he returned to the University of Pittsburgh for 5 years before moving to the University of California at San Diego. After 12 years at UCSD, Dr. Sell took the position as Chair of Pathology and Laboratory Medicine at the University of Texas (UT) at Houston before moving to Albany Medical College. As of February 2003 he has been a senior scientist at Wadsworth Center, a Professor at University at Albany School of Public Health and an Adjunct Professor at Albany College of Pharmacy. Dr. Sell received the Rudolph L. K. Virchow Award of the Italian Medical Magazine LeadershipMedica.com for his concept of cancer stem cells; he was named Legacy Laureate of the University of Pittsburgh for his work on alpha-fetoprotein as a marker for liver cancer; and in 2007 received the Abbott Award of the International Society for Oncodevelopmental Biology and Medicine for recognizing the role of stem cells in carcinogenesis. He has published over 400 papers and 12 books, including 6 editions of Immunology, Immunopathology and Immunity. His paper with Barry Pierce (Lab. Invest. 70:6-21, 1994.) was selected as an AACR scientific landmark.