SICKLE CELL DISEASE IN CLINICAL PRACTICE

- A clear practical guide of how to manage the common acute complications of sickle cell disease including acute pain, stroke and acute chest syndrome
- A clear guide to outpatient management of patients with sickle cell disease, including management plans for the chronic complications of sickle cell disease
- A summary of the published evidence, where available, to support this approach
- A pragmatic approach, offering management algorithms where appropriate

Sickle Cell Disease is the most common genetic disease world wide and in the UK. It has marked geographical variation in its distribution in the UK, with a concentration in London and other major conurbations (Birmingham and Manchester). In these areas, specialist centres have become established offering expert, up to date care for both inpatients and out patients with Sickle Cell Disease.
Although patient numbers are increasing outside these areas, the expertise of health professionals can be patchy. This book aims to provide a user friendly, accessible resource for areas with smaller numbers of patients, to allow them to provide equitable care with the larger well established centres. Sickle Cell Disease can be associated with acute life threatening complications, when clear, easily available advice is needed, and with chronic long term complications which may need liaison with other health professionals. Clear treatment protocols for all the common complications of sickle cell disease, are outlined here, with summaries of key evidence and references.

Author
Jo Howard is Consultant haematologist at the Department of Haematology, Guys & St Thomas' NHS Foundation Trust, London

Table of contents (19 chapters)
1.Overview of Sickle Cell Disease
2.Laboratory Tests Used in Diagnosis and Monitoring
3.Organization of Care
4.Overview and General Principles
5.Pain in Sickle Cell Disease
6.Respiratory and Cardiac Complications
7.Neurological Complications
8.Renal and Urological Complications
9.Bone and Joint Complications in Sickle Cell Disease
10.Ophthalmological Complications
11.The Spleen
12.Infection and Infection Prophylaxis
13.Gastroenterological Complications
14.Anemia and Sickle Cell Disease
15.Leg Ulceration
16.Management of Pregnancy
17.Surgical Management
18.Treatment of Sickle Cell Disease
19.Out-Patient Management