NON-SURGICAL ABLATION THERAPY FOR EARLY-STAGE BREAST CANCER

1. Introduction
2. Evolution of Operative Methods in Japan
3. New Trends and Development in Breast Surgery
4. A Theory of Radiofrequency Ablation (RFA)
5. RFA of Breast Cancer: Criteria and Procedure
6. RFA of Breast Cancer: Technique 1, Requisite Skills and Pitfalls to Avoid
7. RFA of Breast Cancer: Technique2, Knack and Pitfall
8. Histopathological Evaluation of the Therapeutic Effect of RFA for Early Breast Cancer
9. Importance of Breast Imaging Before and After RFA Therapy
10. Cosmetic Evaluation of RFA
11. RFA of Breast Cancer: A Multicenter Retrospective Analysis
12. RFA with a Cool-Tip Electrode in Early Breast Cancer
13. RFA with a LeVeen Needle Electrode in Early Breast Cancer
14. RFA of Early Breast Cancer Followed by Delayed Surgical Resection
15. RFA of Early Breast Cancer Without Resection
16. Prospective Study of RFA of Early Breast Cancer Without Resection
17. MRI-Guided Focused Ultrasound Surgery of Breast Cancer
18. Ultrasonography Guided Nonsurgical Cryoablation for Small Breast Cancer
19. Importance of Breast Imaging Before and After Nonsurgical Ablation Therapy
20. Future and Development of Nonsurgical Ablation of Breast Cancer

Covering the history of breast cancer, theory of radiofrequency ablation (RFA), resection of carcinoma, imaging before and after non-surgical ablation therapy and quality of life, this book focuses on extensive breast-conserving treatment for the preservation of a cosmetically acceptable breast. It investigates the feasibility of percutaneous, minimally invasive techniques to ablate breast tumors and several modalities such as cryosurgery, laser ablation, thermoablation and high-intensity focused ultrasound. Non-surgical Ablation Therapy for Early-stage Breast Cancer centers on RFA and provides insights into cryoablation and focused ultrasound surgery.
RFA has been shown to be effective for treating tumors in many types of tissue, including liver, bone, brain, kidney, pancreas and prostate. As such this book is a valuable resource for breast and general surgeons, radiation oncologists and medical oncologists in all areas. The extensive discussions enable scholars to gain radiological expertise and a basic understanding of molecular biology, leading to better surgery without scalpels.

Features
• Presents the history of breast cancer, theory of RFA, resection of carcinoma, imaging before and after non-surgical ablation therapy and QOL.
• Extensively discusses breast-conserving treatment, including radiofrequency ablation (RFA), cryoablation and focused ultrasound surgery
• Discusses new trends and advances in breast cancer surgery and the future development of non-surgical ablation of breast cancer

Author
Takayuki Kinoshita, M.D, Ph.D Chief, Division of Breast Surgery National Cancer Center Hospital, Chuo-ku, Tokyo, Japan