NEW WEAPONS TO CONTROL BACTERIAL GROWTH

1. Introductory Chapter
Villa, Tomás G. (et al.)
Pages 1-13
2. Antimicrobial Peptides Produced by Bacteria: The Bacteriocins
Martínez, Beatriz (et al.)
Pages 15-38
3. Control of Bacterial Growth Through RNA Degradation
Villa, Tomás G. (et al.)
Pages 39-82
4. Control of
Johnson, Eric A.
Pages 83-93
5. DNA-Synthesizing Enzymes as Antibacterial Targets
Barreiro, Carlos (et al.)
Pages 95-114
6. Mechanisms of Drug Efflux and Strategies to Overcome Them as a Way to Control Microbial Growth
Miguel, T. (et al.)
Pages 115-132
7. Bacterial Proteases as Targets to Control Bacterial Growth
Ullán, Ricardo V. (et al.)
Pages 133-159
8. Quorum Sensing as Target for Antimicrobial Chemotherapy
Vicente-Soler, Jerónima (et al.)
Pages 161-184
9. The Case of Lipid II: The Achilles’ Heel of Bacteria
Villa, Tomás G. (et al.)
Pages 185-217
10. Microbiome Control in the Prevention and Early Management of Cancer
Nguewa, Paul A. (et al.)
Pages 219-237
11. Targets Against
Neelapu, Nageswara Rao Reddy (et al.)
Pages 239-279
12. Intestinal Microbiota: First Barrier Against Gut-Affecting Pathogens
Calo-Mata, Pilar (et al.)
Pages 281-314
13. Fecal Matter Implantation as a Way to Fight Diarrhea-Causing Microorganisms
Villa, Tomás G. (et al.)
Pages 315-352
14. Human Mutations Affecting Antibiotics
Villa, Tomás G. (et al.)
Pages 353-393
15. Different Approaches for Searching New Microbial Compounds with Anti-infective Activity
Centeno-Leija, Sara (et al.)
Pages 395-431
16. Therapeutic Potential of Antimicrobial Peptides
Rabanal, Francesc (et al.)
Pages 433-451
17. The Use of Nanoparticles for Antimicrobial Delivery
Moreno-Sastre, María (et al.)
Pages 453-487
18. Bacterial Predation: Natural Guns to Control Infection
Berlanga, Mercedes (et al.)
Pages 489-508
19. The Biological Fight Against Pathogenic Bacteria and Protozoa
Villa, Tomás G. (et al.)
Pages 509-556

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages or purified lysins), the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.

Features
• Reviews the “state of the art” of alternative treatment strategies and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms
• Suggests new research approaches
• Provides insights into avoiding antimicrobial resistance

Authors
• Tomás G. Villa. Department of Microbiology, Biotechnology Unit, Faculty of Pharmacy, University of Santiago de Compostela, Spain
• Miguel Viñas. Dept. Pathology and Experimental Therapeutics, Faculty of Medicine, University of Barcelona, Spain