NEUROENDOCRINE TUMOR PATHOLOGY AND MOLECULAR DIAGNOSIS. A CASE BASED REVIEW

• Written by an outstanding team of practicing neuroendocrine pathologists and oncologists
• Case-based review format provides practical diagnostic and therapeutic approach
• Focuses on the newer histological grading schemes of the major neuroendocrine societies

This text brings together the diagnostic and clinical expertise of an outstanding team of practicing neuroendocrine pathologists and oncologists. The case-based review format provides a practical diagnostic and therapeutic approach to illustrate real-life examples of a diverse range of neuroendocrine tumors that were diagnosed and worked-up in the multi-disciplinary setting of one of the leading academic cancer centers in the United States. In addition to the clinic-pathologic and molecular advances in the field of neuroendocrine oncology, this book focuses on the newer histological grading schemes by the North American NeuroEndocrine Tumor Society (NANETS), European NeuroEndocrine Tumor Society (ENETS) and the World Health Organization (WHO) and the recently proposed pathologic staging systems by the AJCC, WHO and ENETS. Individual case discussions are integrated with pertinent progress in molecular characterization of these unusual neoplasms. The balanced case content allows the reader to develop a comprehensive and practical understanding of the current trends in the pathology and molecular diagnosis of neuroendocrine neoplasms.
Neuroendocrine Tumor Pathology and Molecular Diagnosis: A Case Based Review will be of great value to anatomic pathology (histopathology)residents, fellows, surgical pathologists, oncologists and surgeons in academia and community settings.


Contents
•Section I: General Topics in Neuroendocrine Tumor Pathology.
- 1. Current Grading of the Neuroendocrine Neoplasms.
- 2. Current Staging of the Neuroendocrine Neoplasms.
- 3. Differential Diagnosis of the Neuroendocrine Neoplasms.
- 4. Immunohistochemistry of the Neuroendocrine Neoplasms.
- 5. Poorly-Differentiated Neuroendocrine Carcinoma.
• Section II: Systemic Aspects of Neuroendocrine Tumor Pathology.
- 6. Neuroendocrine Carcinoma of the Brain.
- 7. Medullary Carcinoma of the Thyroid.
- 8. Neuroendocrine Carcinoma of the Thymus.
- 9. Neuroendocrine Neoplasm of the Lung.
- 10. Neuroendocrine Carcinoma of the Breast.
- 11. Neuroendocrine Neoplasms of the Esophagus.
- 12. Neuroendocrine Neoplasms of the Stomach.
- 13. Neuroendocrine Neoplasms of the Pancreas.
- 14. Neuroendocrine Neoplasms of the Small Intestine.
- 15. Neuroendocrine Neoplasms of the Appendix.
- 16. Neuroendocrine Neoplasms of the Colon.
- 17. Neuroendocrine Tumors of the Adrenal Gland.
- 18. Neuroendocrine Carcinoma of the Bladder.
- 19. Neuroendocrine Carcinoma of the Prostate.
- 20. Neuroendocrine Tumors of the Female Reproductive System.
- 21. Neuroendocrine Tumors of the Skin.
- 22 . Extraskeletal Ewing's Sarcoma-Primitive Neuroectodermal Tumor.
• Section III: Molecular & Therapeutic Advances in Neuroendocrine Tumor Pathology.
- 23. Molecular Pathology of Neuroendocrine Tumors in the Era of Targeted Therapeutics.
- 24. Somatostatin Receptors in Neuroendocrine Tumors.
- 25. Pathologic Angiogenesis in Neuroendocrine Tumors.
- 26. Molecular Targets in Neuroendocrine Tumor Pathology.
- 27. Molecular Biomarkers in Neuroendocrine Tumor Pathology.
- 28. Targeted Therapies for Neuroendocrine Neoplasms.
- 29. Future Directions in Neuroendocrine Tumor Pathology.