IMAGE-GUIDED HYPOFRACTIONATED STEREOTACTIC RADIOSURGERY. A PRACTICAL APPROACH TO GUIDE TREATMENT OF BRAIN AND SPINE TUMORS

• Invited Perspectives on Hypofractionated Stereotactic Radiosurgery
Yoshiya Yamada, Martin Brown, and Brian D. Kavanagh
• Tumor Vascular Conundrum: Hypoxia, Ceramide, and Biomechanical Targeting of Tumor Vasculature
Ahmed El Kaffas and Gregory J. Czarnota
• Gamma Knife: From Single-Fraction SRS to IG-HSRT
Daniel M. Trifiletti, Jason P. Sheehan, and David Schlesinger
• CyberKnife Image-Guided Hypofractionated Stereotactic Radiotherapy
Christopher McGuinness, Martina Descovich, and Igor Barani
• Linac-Based IG-HSRT Technology
Richard Popple
• Advanced MRI for Brain Metastases
Michael Chan, Paula Alcaide Leon, Sten Myrehaug, Hany Soliman, and Chris Heyn
• From Frame to Frameless: Brain Radiosurgery
Young Lee and Steven Babic
• Principles of Image-Guided Hypofractionated Stereotactic Radiosurgery for Brain Tumors
Kevin D. Kelley, Mihaela Marrero, and Jonathan P.S. Knisely
• Principles of Image-Guided Hypofractionated Radiotherapy of Spine Metastases
Johannes Roesch, Stefan Glatz, and Matthias Guckenberger
• Spine Stereotactic Body Radiotherapy for the Treatment of De Novo Spine Metastasis
Ehsan H. Balagamwala, Jacob Miller, Lilyana Angelov, John H. Suh, Simon S. Lo, Arjun Sahgal, Eric L. Chang, and Samuel T. Chao
• Image-Guided Hypofractionated Stereotactic Radiotherapy for Reirradiation of Spinal Metastases
Nicholas Trakul, Sukhjeet S. Batth, and Eric L. Chang
• IG-HSRT for Benign Tumors of the Spine
Peter C. Gerszten and John C. Flickinger
• Postoperative Spine IG-HSRT Outcomes
Ariel E. Marciscano and Kristin J. Redmond
• Postoperative Cavity Image-Guided Stereotactic Radiotherapy Outcomes
Mary Frances McAleer and Paul D. Brown
• Brain Metastases Image-Guided Hypofractionated Radiation Therapy: Rationale, Approach, Outcomes
John M. Boyle, Paul W. Sperduto, Steven J. Chmura, Justus Adamson, John P. Kirkpatrick, and Joseph K. Salama
• Image-Guided Hypofractionated Stereotactic Whole-Brain Radiotherapy and Simultaneous Integrated Boost for Brain Metastases
Alan Nichol
• Image-Guided Hypofractionated Radiation Therapy for High-Grade Glioma
John Cuaron and Kathryn Beal
• Benign Brain Tumors
Or Cohen-Inbar and Jason P. Sheehan
• Radiation Necrosis
Kenneth Y. Usuki, Susannah Ellsworth, Steven J. Chmura, and Michael T. Milano
• Vertebral Compression Fracture Post–Spine SBRT
Isabelle Thibault, Samuel Bergeron Gravel, Cari Whyne, David Mercier, and Arjun Sahgal
• Spinal Cord Dose Limits for Stereotactic Body Radiotherapy
Ahmed Hashmi, Hiroshi Tanaka, Shun Wong, Hany Soliman, Sten Myrehaug, Chia-Lin Tseng, Simon S. Lo, David Larson, Arjun Sahgal, and Lijun Ma
• Summary of Image-Guided Hypofractionated Stereotactic Radiotherapy: Serious Late Toxicities and Strategies to Mitigate Risk
Simon S. Lo, Kristin J. Redmond, Nina A. Mayr, William T. Yuh, Zhibin Huang, Eric L. Chang, Bin S. Teh, and Arjun Sahgal

• Gives a complete guide to state-of-the-art technology development and practice guidelines for hypofractionated SRT for metastatic brain and spine tumors
• Addresses current standards of practice with checklists included
• Covers spine radiosurgery on post-operative applications
• Includes a section on radiobiology

This book offers an up-to-date, practical guide to hypofractionated SRT for brain and spine metastases, as well as other tumor types such as glioma and benign tumors. The recent development of hypofractionated SRT, which calls for 1 to 5 fractions of high dose radiation to be delivered using special equipment, has resulted in the need for education on practice guidelines. This how-to guide emphasizes the pros and cons of hypofractionated SRT compared to single fraction radiosurgery.

Authors
• Arjun Sahgal, Department of Radiation Oncology, University of Toronto, and Sunnybrook Research Institute, Ontario, Canada.
• Simon S. Lo, Department of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
• Lijun Ma, Department of Radiation Oncology, University of California, San Francisco, USA.
• Jason P. Sheehan, Department of Neurological Surgery, University of Virginia, Charlottesville, USA