HAEMATOLOGY IN CRITICAL CARE

Issues of thrombosis, bleeding, and transfusion are extremely common, and often complex, in critically ill patients.
Haematology in Critical Care: A Practical Handbookprovidesa dependable source of expert guidance on how to handle common haematological problems seen in the critical care setting, as well as the acute care of patients with a primary haematological disorder.
Full-time clinical haematologists, regularly attending on intensive care, the Editors begin with an approach to abnormal laboratory tests, following with a disease-orientated approach to topics such as coagulation and haematological malignancy. Other key topics include paediatric and neonatal care, transfusion, point of care testing and the emergency presentation of haematological disease.
This title brings together two of the most highly scientific specialties in clinical practice, delivering a practical approach to these problems, and guiding the clinician through the diagnosis and management of common scenarios encountered in the ICU.

Contents
Section 1 Approach to Abnormal Blood Tests
1 Diagnostic Approach to Anaemia in Critical Care, 3
2 Leukopenia, 9
3 Thrombocytopenia in the Intensive Care Unit, 12
4 High Blood Counts, 16
5 The Abnormal Clotting Profile, 26
6 Understanding the Blood Film, 31

Section 2 Approach to Coagulation Problems
7 Venous Thromboembolism in Intensive Care, 39
8 Reversal and Monitoring of Anticoagulants, 45
9 Disseminated Intravascular Coagulation, 52
10 Heparin-Induced Thrombocytopenia, 58
11 Thrombotic Microangiopathies, 62
12 Critical Care of Patients with a Congenital Bleeding Disorder, 69

Section 3 Approach to Transfusion Problems
13 Blood Components and Their Contents, 77
14 Transfusion Reactions, 86
15 The Management of Non-traumatic Massive Haemorrhage, 93
16 Plasma Exchange, 100

Section 4 Approach to Red Cell Problems
17 Appropriate Haemoglobin in Intensive Care, 107
18 Sickle Cell Disease and Thalassaemia in the Critical Care Setting, 112
19 Management of Patients Who Refuse Blood Transfusion, 118

Section 5 Approach to White Cell Problems
20 Infectious Complications in the Immunosuppressed Patient, 125
21 Haematopoietic Stem Cell Transplantation (HSCT), 135
22 Multiple Myeloma and Hyperviscosity Syndrome, 144
23 Palliative Care for the Patient with Haematological Malignancy in Intensive Care, 148

Section 6 Admission to Intensive Care
24 Haematological Malignancy Outside Intensive Care: Current Practice and Outcomes, 159
25 Early Care of the Unstable Patient: Preventing Admission to the Intensive Care Unit, 165
26 Decisions to Intensify Treatment: Who Will Benefit from Intensive Care?, 171

Section 7 Point-of-Care Testing
27 The Relevance of Thromboelastography in Intensive Care Patients, 179
Section 8 Haematology Drugs in Critical Care
28 Recombinant Activated Coagulation Factor VII (rFVIIa) in Critical Care, 187
29 The Use of Haemostatic Drugs in Post-operative Bleeding, 192
30 Delivering Chemotherapy on Intensive Care, 196

Section 9 Haematology in Paediatric and Neonatal Intensive Care
31 Neonatal Anaemia, 207
32 Haemolysis, 213
33 Approach to Thrombocytopenia, 219
34 Blood Component Therapy in Children and Neonates, 224
Section 10 Haematological Emergencies
35 Haematological Emergencies, 235
Appendix A: Adult, Paediatric and Neonatal Haematology Reference Intervals, 243
Index, 249