ESSENTIALS OF PHARMACOLOGY FOR ANESTHESIA, PAIN MEDICINE, AND CRITICAL CARE

- FDA “black box” warnings
- Basic principles and practical clinical information, e.g., indications, side effects, dosing, and drug interactions
- Concepts and medications frequently tested on standardized exams
- Designed for daily consultation
- Suitable for practitioners, trainees, and students

In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base, and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) “black box” warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians.

Authors
- Alan David Kaye. Departments of Anesthesiology and Pharmacology,. LSU Health Sciences Center, New Orleans, LA, USA;. LSU Interim Hospital and Ochsner Kenner Hospital, New Orleans, LA, USA
- Adam M. Kaye. Department of Pharmacy Practice,. Thomas J. Long School of Pharmacy and Health Sciences,. University of the Pacific. Stockton, CA, USA.
- Richard D. Urman. Department of Anesthesia, Harvard Medical School. Hospital Procedural Sedation Management and Safety,. Center for Perioperative Management and Medical Informatics,. Brigham and Women’s Hospital. Boston, MA, USA.

Table of contents (55 chapters)
1.Pharmacokinetics and Pharmacodynamics of Anesthetics
2.A Review of Mechanisms of Inhalational Anesthetic Agents
3.Pharmacokinetics, Pharmacodynamics, and Physical Properties of Inhalational Agents
4.Principles of Total Intravenous Anesthesia
5.Perioperative Considerations in Pharmacology
6.Anesthetic Induction Agents
7.Analgesics: Opiate Agonists, Mixed Agonists/Antagonists, and Antagonists for Acute Pain Management
8.Analgesics: Opioids for Chronic Pain Management and Surgical Considerations
9.Nonopioid Analgesic and Adjunct Drugs
10.Benzodiazepines and Muscle Relaxants
11.Pharmacology of Local Anesthetics
12.Neuromuscular Blockers
13.Reversal Agents
14.Drugs Acting on the Autonomic Nervous System
15.Antihypertensives, Diuretics, and Antidysrhythmics
16.Peripheral Vasodilators
17.Nitric Oxide and Pulmonary Vasodilators
18.Asthma and COPD Agents
19.Hormones, Part 1: Thyroid and Corticosteroid Hormones
20.Hormones Part 2: Insulin and Other Glucose-Controlling Medications
21.Antacids, Gastrointestinal Prokinetics, and Proton Pump Inhibitors
22.Histamine Modulators
23.Central Nervous System Stimulants
24.Anticoagulant Drugs
25.Hemostatic Agents
26.Blood, Blood Products, and Substitutes
27.Antipyretics: Acetaminophen, Arachidonic Acid Agents, and COX1 and COX2 Inhibitors
28.Antiemetic Agents
29.Antiepileptic Agents
30.Neuropharmacologic Agents for Neurologic Conditions
31.Chemotherapeutic Agents
32.Antimicrobial Agents
33.Herbal Medications and Vitamin Supplements
34.Minerals and Electrolytes
35.Disinfection Agents and Antiseptics
36.Psychopharmacologic Agents and Psychiatric Drug Considerations
37.Cocaine, Methamphetamine, MDMA, and Heroin
38.Cardiac Surgery
39.The Intensive Care Unit
40.Enteral and Parenteral Nutrition
41.Obstetrics
42.Pediatrics
43.Neurologic Surgery
44.Liver Disease and Liver Transplantation
45.Black Box FDA Warnings and Legal Implications
46.Drug-Induced QT Prolongation
47.Drugs and Cancer Propagation
48.Lipid-Lowering Agents
49.Serotonin Syndrome
50.Novel Psychoactive Substances: Synthetic Cathinones and Cannabinoid Receptor Agonists
51.New Vistas in Anesthetics, IV Induction Agents
52.New Vistas in Neuromuscular Blockers
53.Patient-Controlled Analgesia: The Importance of Effector Site Pharmacokinetics
54.Understanding Anesthesia-Induced Memory Loss
55.Novel Targets of Current Analgesic Drug Development