DISEASES OF THE KIDNEY

Section I Structural and Functional Correlations in the Kidney

1. Structural---Functional Relationships in the Kidney
Robert F. Reilly Jr., Ruth Ellen Bulger, Astrid Weins, and Wilhelm Kriz

2. Clinical Importance of Nephron Mass
Valerie A. Luyckx and Thomas F. Mueller

3. Renal Circulation and Glomerular Hemodynamics
William J. Arendshorst and L. Gabriel Navar


4. Regulation of Water Balance: Urine Concentration and Dilution
Yumi Noda and Sei Sakaki

5. Tubular Sodium Transport
Arohan R. Subramanya, Núria M. Pastor-Solar, W. Brian Reeves, and Kenneth R. Hallows

6. Tubular Potassium Transport
David B. Mount

7. Renal Acid---Base Transport
Thomas D. DuBose Jr. and Amanda K. Goode

8. Hormones and the Kidney
Sola Aoun Bahous, Maya Khairallah, Joumana T. Chaiban, and Kamal F. Badr



Section II Clinical Evaluation

9. Laboratory Evaluation of Kidney Disease
Lesley A. Inker, Richard A. Lafayette, Ashish Upadhyay, and Andrew S. Levey

10. Ultrasonography and Nuclear Medicine
Frederic Rahbari-Oskoui, Andrew T. Taylor, and William Charles O’Neill

11. Computed Tomography and Magnetic Resonance Imaging
Kyongtae Bae and Sonal Krishan

12. Diagnostic Angiography and Therapeutic Endovascular Intervention of the Renal Circulation
Alex Perino, Rajan Gupta, and Ivan P. Casserly

13. Renal Biopsy: Indications and Evaluation
I. David Weiner, C. Craig Tisher, and Byron P. Croker


Section III Cystic and Tubular Disorders


14. Introduction to Genetic Renal Disease
Erum Hartung, Terry Watnick, and Gregory G. Germino

15. Nephronophthisis-Medullary Cystic Kidney Disease
Friedhelm Hildebrandt, Rannar Airik, and John A. Sayer

16. Autosomal Dominant Polycystic Kidney Disease
Stefan Somlo and Arlene B. Chapman

17. Alport Syndrome, Fabry Disease, and Nail-Patella Syndrome
Godela M. Brosnahan, Martin Gregory, Imed Halal, and Berenice Y. Reed

18. Isolated Renal Tubular Disorders: Mechanisms and Clinical Expression
Thomas D. DuBose Jr. and Amanda K. Goode

19. Urinary Tract Obstruction and Reflux Nephropathy
Ryan B. Pickens and Edward D. Kim

20. Nephrolithiasis
Keith A. Hruska and Anne M. Beck

Section IV Infections of the Urinary Tract and the Kidney

21. Host-Pathogen Interactions and Host Defense Mechanisms
Keira Melican, Ferdinand X. Choong, and Agneta Richter-Dahlfors

22. Cystitis and Urethritis
Annelie Brauner and Milan Chromek

23. Infections of the Upper Urinary Tract
Lindsay E. Nicollé

24. Renal and Perirenal Abscesses
Neha D. Nanda and Louise M. Dembry

25. Complicated Urinary Tract Infections
Dennis J. Mikolich* and Stephen H. Zinner

26. Fungal Infections of the Urinary Tract
Carol A. Kauffman

27. Urinary Tract Tuberculosis
Mark S. Pasternack and Robert H. Rubin


Section V Acute Kidney Injury

28. Epidemiology, Diagnosis and Therapy of Acute Kidney Injury
Etienne Macedo and Ravindra L. Mehta

29. Pathophysiology of Ischemic Acute Kidney Injury
Charles L. Edelstein and Robert W. Schrier

30. Pathophysiology of Nephrotoxic Cell Injury
Brian S. Cummings and Rick G. Schnellmann

31. Antibiotic- and Immunosuppression-Related Renal Failure
Marc E. De Broe

32. Nephrotoxicity of Nonsteroidal Antiinflammatory Agents, Analgesics,
and Inhibitors of the Renin-Angiotensin System
Biff F. Palmer

33. Contrast-Induced Acute Kidney Injury
Steven D. Weisbord and Paul M. Palevsky

34. Nephrotoxicity Secondary to Environmental Agents, Heavy Metals, Drug Abuse, and Lithium
Veronica Torres da Costa e Silva, Etienne Macedo, and Luis Yu

35. Acute Tubulointerstitial Nephritis
Garabed Eknoyan and Rajeev Raghavan

36. Acute Kidney Injury Associated with Pigmenturia or Crystal Deposits
Abolfazl Zarjou and Anupam Agarwal

37. Acute Kidney Injury Secondary to Tropical Hemorrhagic Viral Infections and Snakebite
Emmanuel A. Burdmann

38. Acute Kidney Injury Following Hematopoietic Cell Transplantation and Severe Burns
Justin Belcher and Chirag R. Parikh



Section VI Hypertension

39. Role of the Kidneys in Hypertension
Joey P. Granger and Eric M. George

40. Hypertension in Chronic Kidney Disease
Peter N. Van Buren and Robert D. Toto

41. Hypertension in End-Stage Kidney Disease
Rajiv Agarwal

42. Renal Artery Stenosis, Renovascular Hypertension, and Ischemic Nephropathy
Stephen C. Textor

43. Hypertension Due to Primary Aldosteronism and Related Disorders
Emmanuel L. Bravo, Muhammed A. Rafey, and Surafel F. Gebreselassie

44. Malignant Hypertension and Other Hypertensive Crises
Charles R. Nolan and Stuart L. Linas


Section VII Glomerular, Interstitial, and Vascular Renal Diseases

45. Mechanisms of Immune Glomerular Injury
William G. Couser

46. Acute Infectious Glomerulonephritis: Including Post-streptococcal and Other Bacterial Infection---Related Glomerulonephritis
Laura L. Mulloy and Michael P. Madaio

47. Viral Glomerulonephritis
Warren Kupin

48. Vasculitic Diseases of the Kidney
Julieanne G. McGregor, Patrick H. Nachman, J. Charles Jennette, and Ronald J. Falk

49. Immunoglobulin A Nephropathy and Henoch-Schönlein Purpura
Jan Novak and Bruce A. Julian

50. Membranoproliferative Glomerulonephritis and Dense Deposit Disease
J. Ashley Jefferson, Miguel Palma-Diaz, and Charles E. Alpers

51. Membranous Nephropathy
Laurence Beck, Jr. and David Salant

52. Nephrotic Syndrome and the Podocytopathies: Minimal Change Nephropathy, Focal Segmental Glomerulosclerosis, and Collapsing Glomerulopathy
H. William Schnaper and Jeffrey B. Kopp

53. Renal Involvement in Systemic Lupus Erythematosus
Brad H. Rovin, Daniel J. Birmingham, and Tibor Nadasdy

54. Systemic Sclerosis, Rheumatoid Arthritis, Sjögren Syndrome, and Polymyositis-Dermatomyositis
Meryl Waldman, James E. Balow, and Howard A. Austin III

55. Hemolytic-Uremic Syndrome, Thrombotic Thrombocytopenic Purpura, and Acute Cortical Necrosis
Marina Noris, Giuseppe Remuzzi, and Piero Ruggenenti

56. Renal Artery Thrombosis, Thromboembolism, Aneurysms, Atheroemboli and Renal Vein Thrombosis
John W. O’Bell, George P. Bayliss, and Lance D. Dworkin

57. Chronic Tubulointerstitial Nephritis
Allison A. Eddy and Ikuyo Yamaguchi


Section VIII Systemic Diseases of the Kidney

58. Clinical Aspects of Diabetic Nephropathy
Jamie P. Dwyer and Julia B. Lewis

59. The Normal and Diseased Kidney in Pregnancy
Michelle A. Hladunewich, Ayodele Odutayo, and Ravi Thadhani

60. Monoclonal Gammopathies: Multiple Myeloma, Amyloidosis, and Related Disorders
Pierre Ronco, Frank Bridoux, and Pierre Aucouturier

61. Hyperuricemia, Gout, and the Kidney
Duk-Hee Kang, Mehmet Kanbay, and Richard Johnson

62. Sickle Cell Disease
Vimal K. Derebail and Abhijit V. Kshirsagar

63. Tropical Nephrology
Rashad S. Barsoum, Tarek Fayad, Kearkiat Praditpornsilpa, and Visith Sitprija

64. A Clinical Approach to Kidney Disease in Infants, Children, and Adolescents
Craig B. Langman, Gal Finer, and Neziha Celebi

65. Renal Function and Disease in the Aging Kidney
Ramesh Saxena, Andrew Fenves, Xueqing Yu, Nosratola D. Vaziri, Fred G. Silva, and Xin J. Zhou


Section IX Disorders of Electrolyte, Water, and Acid Base

66. Mechanisms of Diuretic Action
David H. Ellison, Ewout J. Hoorn, and Robert W. Schrier

67. Cardiac Failure and the Kidney
William T. Abraham and Robert W. Schrier

68. Liver Disease and the Kidney
Pere Ginès, Andrés Cárdenas, Elsa Solà, and Robert W. Schrier

69. The Nephrotic Syndrome
Jeroen K.J. Deegens, Robert W. Schrier, and Jack F.M. Wetzels

70. The Syndrome of Inappropriate Antidiuretic Hormone Secretion and Other Hypoosmolar Disorders
Joseph G. Verbalis

71. Nephrogenic and Central Diabetes Insipidus
Daniel G. Bichet

72. Disorders of Potassium and Acid-Base Metabolism in Association with Renal Disease
Mark A. Perazella and Asghar Rastegar

73. Disorders of Phosphorus, Calcium, and Magnesium Metabolism
Keith A. Hruska, Moshe Levi, and Eduardo Slatopolsky

74. Fluid-Electrolyte and Acid-Base Disorders Complicating Diabetes Mellitus
Horacio J. Adrogué and Nicolaos E. Madias

Section X Chronic Kidney Disease

75. Pathophysiology and Nephron Adaptation in Chronic Kidney Disease
Radko Komers, Timothy W. Meyer, and Sharon Anderson

76. Anemia in Chronic Kidney Disease
James E. Novak and Jerry Yee

77. Mineral and Bone Disorder in Chronic Kidney Disease
Elvira O. Gosmanova and Darryl L. Quarles

78. Nervous System Manifestations of Renal Disease
Yeong-Hau Howard Lien

79. Cardiac Disease in Chronic Kidney Disease
Patrick S. Parfrey and Sean W. Murphy

80. Metabolic and Endocrine Dysfunctions in Uremia
Eberhard Ritz, Marcin Adamczak, and Andrzej Wiecek

Section XI Management of End-Stage Renal Disease

81. Immunobiology and Immunopharmacology of Renal Allograft Rejection
Choli Hartono, Terry B. Strom, and Manikkam Suthanthiran

82. Clinical Aspects of Renal Transplantation
Alexander C. Wiseman, James E. Cooper, and Laurence Chan

83. Peritoneal Dialysis
Seth Furgeson, Rajnish Mahrotra, John M. Burkart, and Isaac Teitelbaum

84. Hemodialysis
Scott D. Bieber and Jonathan Himmelfarb

85. Dietary Factors in the Treatment of Chronic Kidney Disease
Sreedhar A. Mandayam, William E. Mitch, and Joel D. Kopple

86. Use of Drugs in Patients with Renal Failure
Ali J. Olyaei, Jessica L. Steffl, and William M. Bennett

Index

The recent advances in many aspects of kidney diseases have mandated the ninth edition of Schrier's Diseases of the Kidney. This all-encompassing work provides both clinicians and academicians with information they need to treat and study kidney disorders. Combining basic and clinical sciences, the book provides authoritative, concise, and readily accessible information. About 200 international authorities, guided by a team of five distinguished authorities in nephrology, create an invaluable resource. Dr. Schrier, the long-time sole editor of this work, has recruited four eminent nephrologists as co-editors for this edition.

The book is divided into eleven sections that cover:
•Structural, Functional Correlations in the Kidney
•Clinical Evaluation
•Cystic and Tubular Disorders
•Infections of the Urinary Tract and the Kidney
•Acute Renal Injury
•Hypertension
•Glomerular, Interstitial, and Vascular Renal Diseases
•Systemic Diseases of the Kidney
•Disorders of Electrolyte, Water, and Acid-Base
•Chronic Kidney Disease
•Management of End-Stage Renal Disease
•Content has been consolidated into two volumes

Plus, with this new edition you have FREE online access to the companion website that contains fully searchable text and an image bank so you have access to the content anytime, anywhere.

Features

All chapters have been updated, with particularly extensive changes to areas such as hereditary disease, acute renal failure, and hypertension
Content has been consolidated into two volumes
Expanded editorial team provides in-depth expertise in all areas of nephrology
References available online link to Medline abstracts and to selected full-text articles
Thousands of new references have been added, and obsolete references have been deleted
Book provides information on basic sciences, laboratory diagnosis, and imaging keyed to the needs of clinicians
Each section of the book is designed to be a self-contained "textbook" for an area of neprhology

About the Author(s)

Ronald J. Falk MD
Cardiology Section, Boston City Hospital, Boston, MA

Eric G. Neilson MD
Hugh Jackson Morgan Professor, Chairman, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN

Thomas M. Coffman MD
James R. Clapp Professor of Medicine
Chief, Division of Nephrology
Duke University and Durham VA Medical Centers
Durham, North Carolina
Program Director in Cardiovascular and Metabolic Disorders
Duke-NUS Graduate Medical School
Singapore

Bruce A. Molitoris MD
Professor of Medicine
Indiana University
Roudebush VA Medical Center
Indianapolis, Indiana

Robert W. Schrier
Professor of Medicine
Division of Renal Disease and Hypertension
University of Colorado Health Sciences Center
Aurora, CO